libtextworker supports 2 GUI toolkits: Tkinter and wxPython. Tkinter is the Python bindings of Tcl/Tk, and wxPython is the Python version of wxWidgets - an universal solution for cross-platform GUI apps without being different from the current OS's look.

Both 2 platforms are powerful, one factor for this is how you use it.

Comparison

Toolkit	Installation	The core	Best for...	Limitations
Tkinter	Not from Pypi	Tk toolkit	Python GUI newbies/who want a simple/good interface with themes	Ugly on Linux, some goods are not here yet
wxPython	Get from Pypi	Win32 API, Cocoa, Gtk, Qt	People who want a more powerful application	Takes time to install + learn

Notes:

About Tk(inter)'s ugly UI: many people hate it - you can search the internet about it, and I don't know how to explain how and why. Fortunately, you can get many modern themes around GitHub! Even a workaround for the native Gtk look for Tkinter/Tk has been started years ago. Only one word before we continue: use Tkinter.ttk as much as possible, because ttk widgets are "colored" - better than the default Tkinter one.
About wxPython installation: if Pypi can't find a wheel (it's something like .msi or .deb) for your machine, it will start building one. This is a normal behaviour, but you have to look for the dependencies wxPython needs.
About Tkinter installation: on Windows there's an option in the installer (not MS Store one?). On *NIX, Tkinter is separated from the main Python package.

What about libtextworker?

For Tkinter support: it's here as the libtextworker.interface.tk package.

For wxPython, it's libtextworker.interface.wx.

The support is not really equal for both GUIs.

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